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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Furanodiene, Germacrone
Phytochemical Name Furanodiene (PubChem CID: 636458 )
Anticancer drug Name Germacrone (PubChem CID: 6436348 )
Structure of
Phytochemical		 2D-img
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2D MOL 3D MOL
Structure of
Anticancer Drug		 2D-img
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 719
Ref_1
Pair Name Furanodiene, Germacrone
Disease Info [ICD-11: 2C60] Breast cancer Investigative
Biological Phenomena Inhibition-->Cell proliferation
Gene Regulation Up-regulation Expression BAX hsa581
In Vitro Model MDA-MB-231 Breast adenocarcinoma Homo sapiens (Human) CVCL_0062
MCF-7 Invasive breast carcinoma of no special type Homo sapiens (Human) CVCL_0031
Result Unpredictable and complex interactions among different components in Curcuma WenyujinY.H.Chenet C Ling may exist. The intra-herb interactions should be taken into consideration when attempts are made to interpret the art of TCM formulation or other similar recipes.
03. Reference
No. Title Href
1 Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation. Cell J. 2013 Summer;15(2):160-5. Click
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